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Fevipiprant - CAS# 872365-14-5 419 Ashby CR Jr

SKU: 2089871254

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Fevipiprant - CAS# 872365-14-5 419 Ashby CR JrFevipiprant, CAS No. 872365 14 5, also known as NVP QAW039 or QAW039, is an oral active and potent CRTh2 receptor antagonist and potentially useful for asthma treatment. [(3)H] QAW039 displayed high affinity for the human CRTh2 receptor (1. 14 0. 44 nM) expressed in Chinese hamster ovary cells, the binding being reversible and competitive with the native agonist prostaglandin D2(PGD2). QAW039 was also a potent inhibitor of PGD2 induced cytokine

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Description

Ashby CR Jr

2016 Jun 30

Prinaberel suppresses pro-inflammatory signaling pathway in UVB-induced skin tumors

Formula: C21H32O6

Fevipiprant - CAS# 872365-14-5 419 Ashby CR JrFevipiprant, CAS No. 872365 14 5, also known as NVP QAW039 or QAW039, is an oral active and potent CRTh2 receptor antagonist and potentially useful for asthma treatment. [(3)H] QAW039 displayed high affinity for the human CRTh2 receptor (1. 14 0. 44 nM) expressed in Chinese hamster ovary cells, the binding being reversible and competitive with the native agonist prostaglandin D2(PGD2). QAW039 was also a potent inhibitor of PGD2 induced cytokine

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