Efonidipine Hydrochloride Size:Solid 10 mg 1) and (+/-)alpha-methyl-5-HT-mediated relaxation of

1) and (+/-)alpha-methyl-5-HT-mediated relaxation of the rat jugular vein (pA2 = 9

79(21):10110-22

Chemical Name: N-(6-(4-(3-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)ureido)phenoxy)pyrimidin-4-yl)cyclopropanecarboxamide

126(2):454-463

Efonidipine Hydrochloride Size:Solid 10 mg 1) and (+/-)alpha-methyl-5-HT-mediated relaxation ofEfonidipine Hcl (NZ 105) is a dual T type and L type calcium channel blocker (CCB). IC50 value: Target: calcium channel blockerin vitro: Efonidipine and nifedipine, but not other examined CCBs, also increased the N(6), 2' O dibutyryladenosine 3',5' cyclic monophosphate (dbcAMP) induced StAR mRNA, which reflects the action of adrenocorticotropic hormone, and efonidipine and R( ) efonidipine enhanced the dbcAMP induced DHEA S production in NCI H295R