CCT241533 Hydrochloride - CAS# 1431697-96-9 ropylthiouracil and 50 mg/kg for 18
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CCT241533 Hydrochloride - CAS# 1431697-96-9 ropylthiouracil and 50 mg/kg for 18CCT 241533 dihydrochloride is a potent Chk2 inhibitor (IC50 = 3 nM). It shows >63 fold selectivity for Chk1 over Chk2 and a panel of 84 other kinases. CCT 241533 dihydrochloride inhibits Chk2 activation in response to etoposide induced DNA damage in HT29 cells and blocks ionizing radiation induced apoptosis of mouse thymocytes. Product information CAS Number: 1431697 96 9 Molecular Weight: 478. 94 Formula: C23H28ClFN4O4 Synonym: CCT 241533
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