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Afuresertib - CAS# 1047644-62-1 Catalog No.:M6803-10 KU-0059436

SKU: 58562040772

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Afuresertib - CAS# 1047644-62-1 Catalog No.:M6803-10 KU-0059436Afuresertib, CAS No. 1047644 62 1, also known as GSK 2110183 or GSK 2110183C, is an orally bioavailable inhibitor of the serine threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity. Afuresertib binds to and inhibits the activity of Akt, which may result in inhibition of the PI3K Akt signaling pathway and tumor cell proliferation and the induction of tumor cell apoptosis. Activation of the PI3K Akt signaling pathway is

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Description

KU-0059436

FT-0644594

Biochem Biophys Res Commun

57(8):3205-12

Afuresertib - CAS# 1047644-62-1 Catalog No.:M6803-10 KU-0059436Afuresertib, CAS No. 1047644 62 1, also known as GSK 2110183 or GSK 2110183C, is an orally bioavailable inhibitor of the serine threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity. Afuresertib binds to and inhibits the activity of Akt, which may result in inhibition of the PI3K Akt signaling pathway and tumor cell proliferation and the induction of tumor cell apoptosis. Activation of the PI3K Akt signaling pathway is

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