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Remodelin - Acetyl-transferase NAT10 Inhibitor. CAS# 949912-58-7 size:2 mg solid 8 nM and 5

Remodelin - Acetyl-transferase NAT10 Inhibitor. CAS# 949912-58-7 size:2 mg solid 8 nM and 5

Name: Remodelin - Acetyl-transferase NAT10 Inhibitor. CAS# 949912-58-7 size:2 mg solid 8 nM and 5
Brand: lifelines-uk.org.uk
SKU: 66049962358
Price: 109.00 USD
Availability: InStock
Rating: 4.5697 (9 reviews)

SKU: 66049962358

4.6

USD109.00 USD143.00

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Remodelin - Acetyl-transferase NAT10 Inhibitor. CAS# 949912-58-7 size:2 mg solid 8 nM and 5Remodelin, CAS No. 949912 58 7, is a novel potent and selective inhibitor of the acetyl transferase protein NAT10. It can improve nuclear architecture, chromatin organization, and fitness of both human lamin A C depleted cells and HGPS derived patient cells, and decrease markers of DNA damage in these cells. Using a combination of chemical, cellular, and genetic approaches, acetyl transferase protein NAT10 was identified as the target of Remodelin

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Description

8 nM and 5

4SC-202 shows a broad anti-proliferative activity towards human cancer cell lines with a mean IC50 of 0

resulting in inhibition of ligand-independent leukemic cell proliferation and apoptosis

Berndtsson M

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