Histone Acetyltransferase Inhibitor II 119 EW-7197 Hydrochloride also inhibits the

EW-7197 Hydrochloride also inhibits the epithelial-to-mesenchymal transition (EMT) in both TGFβ-treated breast cancer cells and 4T1 orthotopic-grafted mice

InChi: InChI=1S/C31H38N6O2/c1-6-22(5)37-18-20(3)29-25(30(38)34-17-26-19(2)13-21(4)35-31(26)39)14-24(15-27(29)37)23-7-8-28(33-16-23)36-11-9-32-10-12-36/h7-8

2014 Sep 28

The next generation of epidermal growth factor receptor tyrosine kinase inhibitors in the treatment of lung cancer

Histone Acetyltransferase Inhibitor II 119 EW-7197 Hydrochloride also inhibits theHistone Acetyltransferase Inhibitor II (HAT Inhibitor II, compound 2c) is a potent, selective and cell permeable p300 histone acetyltransferase (HAT) inhibitor with IC50 of 5 M. Histone Acetyltransferase Inhibitor II shows anti acetylase activity in mammalian cells. Product information CAS Number: 932749 62 7 Molecular Weight: 464. 15 Formula: C20H16Br2O3 Synonym: HAT Inhibitor II Chemical Name: (2E,6E) 2,6 bis[(3 bromo 4