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Bleomycin sulfate - CAS# 9041-93-4 0135 The nuclear receptors REV-ERB-α and

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Bleomycin sulfate - CAS# 9041-93-4 0135 The nuclear receptors REV-ERB-α andBleomycin sulfate, CAS No. 9041 93 4, is a mixture of the sulfate salts of basic glycopeptide antineoplastic antibiotics isolated from Streptomyces verticillus. Bleomycin sulfate forms complexes with iron that reduce molecular oxygen to superoxide and hydroxyl radicals which cause single and double stranded breaks in DNA; these reactive oxygen species also induce lipid peroxidation, carbohydrate oxidation, and alterations in prostaglandin synthesis

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Description

The nuclear receptors REV-ERB-α and REV-ERB-β play an integral role in regulating the expression of core clock proteins

Molecular Weight: 240

Small-molecule binding of the axin RGS domain promotes β-catenin and Ras degradation

412:211-221

Bleomycin sulfate - CAS# 9041-93-4 0135 The nuclear receptors REV-ERB-α andBleomycin sulfate, CAS No. 9041 93 4, is a mixture of the sulfate salts of basic glycopeptide antineoplastic antibiotics isolated from Streptomyces verticillus. Bleomycin sulfate forms complexes with iron that reduce molecular oxygen to superoxide and hydroxyl radicals which cause single and double stranded breaks in DNA; these reactive oxygen species also induce lipid peroxidation, carbohydrate oxidation, and alterations in prostaglandin synthesis

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