A 438079 Hydrochloride - CAS# 899431-18-6 Size:Solid 2 mg Formula: C13H25NO
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A 438079 Hydrochloride - CAS# 899431-18-6 Size:Solid 2 mg Formula: C13H25NOA 438079 is a P2X7 receptor antagonist. A438079 protects against acetaminophen induced liver injury by inhibiting p450 isoenzymes, not by inflammasome activation. A 438079 partially but significantly prevented the 6 OHDA induced depletion of striatal DA stores. P2X7R inhibitor A 438079 reduced electrographic and clinical seizure severity during status epilepticus and reduced seizure induced neuronal death in the neocortex. Blockade of P2X(7) receptors
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