p300(Phospho Ser89) Polyclonal Antibody, 20ul Organelle Studies Heterozygous loss-of-function mutations in this

Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype

Weakly expressed in the brain

PPARs are nuclear hormone receptors that bind peroxisome proliferators and control the size and number of peroxisomes produced by cells

The protein encoded by this gene is highly expressed in peripheral blood of patients with atopic dermatitis (AD)| compared to normal individuals

p300(Phospho Ser89) Polyclonal Antibody, 20ul Organelle Studies Heterozygous loss-of-function mutations in thisThis gene encodes the adenovirus E1A associated cellular p300 transcriptional co activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co activator of HIF1A (hypoxia inducible factor 1