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Tamibarotene - CAS# 94497-51-5 oxifen citrate 10-Formyldihydrofolate is a Methotrexate metabolite

Tamibarotene - CAS# 94497-51-5 oxifen citrate 10-Formyldihydrofolate is a Methotrexate metabolite

Name: Tamibarotene - CAS# 94497-51-5 oxifen citrate 10-Formyldihydrofolate is a Methotrexate metabolite
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Tamibarotene - CAS# 94497-51-5 oxifen citrate 10-Formyldihydrofolate is a Methotrexate metaboliteTamibarotene, also known as SY 1425, is an orally active, synthetic retinoid, developed to overcome all trans retinoic acid (ATRA) resistance, with potential antineoplastic activity. As a specific retinoic acid receptor (RAR) alpha beta agonist, tamibarotene is approximately ten times more potent than ATRA in inducing cell differentiation and apoptosis in HL 60 (human promyelocytic leukemia) cell lines in vitro. Due to a lower affinity for cellular

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Description

10-Formyldihydrofolate is a Methotrexate metabolite

functioning as an inhibitor of matrix metalloproteinases

[Epub ahead of print] PubMed PMID: 27364361

Formula: C22H22N6O3

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