SCH900776 Size:Solid 10 mg is a dual antagonist of

is a dual antagonist of the A2aR and A2bR adenosine receptors

Co-culture of hepatocellular carcinoma cells and human umbilical endothelial cells damaged by SU11274

also known asCX 295

CAS Number: 29110-47-2

SCH900776 Size:Solid 10 mg is a dual antagonist ofSCH900776, also known as MK 8776. is an agent targeting cell cycle checkpoint kinase 1 (Chk1) with potential radiosensitization and chemosensitization activities. Chk1 inhibitor SCH 900776 specifically binds to and inhibits Chk1, which may result in tumor cells bypassing Chk1 dependent cell cycle arrest in the S and G2 M phases to undergo DNA repair prior to entry into mitosis; tumor cells may thus be sensitized to the DNA damaging effects of ionizing