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Bazedoxifene acetate Catalog No.:M10044-2 92 µM toward JMJD2E

Bazedoxifene acetate Catalog No.:M10044-2 92 µM toward JMJD2E

Name: Bazedoxifene acetate Catalog No.:M10044-2 92 µM toward JMJD2E
Brand: lifelines-uk.org.uk
SKU: 84727722454
Price: 80.00 USD
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SKU: 84727722454

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Bazedoxifene acetate Catalog No.:M10044-2 92 µM toward JMJD2EBazedoxifene, also known as WAY 140424, is a third generation selective estrogen receptor modulator (SERM), developed by Pfizer following the completion of their takeover of Wyeth Pharmaceuticals. In late 2013, Pfizer received approval for bazedoxifene as part of the combination drug DUAVEE in the prevention (not treatment) of postmenopausal osteoporosis. Bazedoxifene is an indole based ER ligand that binds to both ER (IC50 = 26 nM) and ER (IC50 = 99

Store: lifelines-uk.org.uk · Domain: lifelines-uk.org.uk

Description

92 µM toward JMJD2E

ClH/c1-20-7-5-13(23-26-10-9-22)11-17(20)18(24)12-14-15-3-4-19(25)21(15

GDC-0068 was orally dosed to mice at 50-100 mg/kg once per day

J Pharm Sci

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