ON-01910 Catalog No.:M7902-10 CAS Number: 1414854-42-4

CAS Number: 1414854-42-4

is a potent and selective constrictive remodeling regulator on renarrowing after balloon overstretch injury of porcine coronary artery

InChi: InChI=1S/C43H51NO14/c1-22-26(55-37(51)32(48)30(24-15-11-9-12-16-24)44-38(52)58-39(3

Kennaway DJ

ON-01910 Catalog No.:M7902-10 CAS Number: 1414854-42-4ON 01910 is a synthetic benzyl styryl sulfone analogue with potential antineoplastic activity. Polo like kinase 1 inhibitor ON 01910. Na inhibits polo like kinase1 (Plk1), inducing selective G2 M arrest followed by apoptosis in a variety of tumor cells while causing reversible cell arrest at the G1 and G2 stage without apoptosis in normal cells. This agent may exhibit synergistic antitumor activity in combination with other chemotherapeutic agents.