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BRD PHOTAC-I-3 Size:2mg solid is a very potent and

BRD PHOTAC-I-3 Size:2mg solid is a very potent and

Name: BRD PHOTAC-I-3 Size:2mg solid is a very potent and
Brand: lifelines-uk.org.uk
SKU: 94624904254
Price: 207.50 USD
Availability: InStock
Rating: 4.0288 (21 reviews)

SKU: 94624904254

4.0

USD207.50 USD227.50

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BRD PHOTAC-I-3 Size:2mg solid is a very potent andBRD PHOTAC I 3 is a photoswitchable BET bromodomain degrader (PHOTAC, PHOtochemically TArgeting Chimera). BRD PHOTAC I 3 comprises a ligand for an E3 ligase, a photoswitch, and the BET bromodomain targeting ligand (+) JQ1 (Cat. No. 4499). Exhibits cytotoxicity and degrades BRD4, BRD3 and to a lesser extent BRD2 in lymphoblast cells upon irradiation with 390 nm light, but not in the dark. Product information CAS Number: 2370997 94 5 Molecular Weight:

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Description

is a very potent and highly selective Wnt signaling antagonist with an IC50 ~ 74 pM in the Wnt signaling reporter assay

PRMT6 and PRMT8

Schiemann K

440(4):701-6

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