Clonidine Hydrochloride Size:Solid 10 mg PubMed PMID: 21620683

PubMed PMID: 21620683

RN-1 was administered by intraperitoneal injection once a day at a dose of 10-30 mg/kg to the novel object recognition (NOR) mouse model

The X-ray structure of SARS-CoV 3CLpro bound with ML188 was instrumental in guiding subsequent rounds of chemistry optimization

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Clonidine Hydrochloride Size:Solid 10 mg PubMed PMID: 21620683Clonidine (also known as Catapres, Kapvay, Nexiclon, and Clophelin) is a sympathomimetic medication used to treat high blood pressure, attention deficit hyperactivity disorder, anxiety disorders, withdrawal (from either alcohol, opioids, or smoking), migraine, menopausal flushing, diarrhea, and certain pain conditions. It is classified as a centrally acting 2 adrenergic agonist and imidazoline receptor agonist that has been in clinical use for over 40