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Adiponectin also decreases hepatic de novo glucose production and reduces free fatty acid levels in the liver (196), thereby mitigating hepatic steatosis, enhancing insulin sensitivity, and improving the circulating lipid profile ( Figure 1 Section E)

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Important Surgical Considerations Exist Interestingly, preoperative GLP-1 RA use was associated with: Increased adhesions between the posterior stomach and pancreas Longer operative times in some cases Higher rates of postoperative nausea and delayed gastric emptying These findings raise important perioperative considerations for surgical teams and anesthesiologists alike