Mouse Beclin 1, BECN1 ELISA Kit, 96T Enzyme-Linked Immunosorbent Assay (ELISA) Attachment of NEDD8 to cullins

Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity

translocates into the mitochondria where it promotes mtDNA transcription

PubMed: 10426996)

which is required for the final step in the soluble A and B antigen synthesis pathway

Mouse Beclin 1, BECN1 ELISA Kit, 96T Enzyme-Linked Immunosorbent Assay (ELISA) Attachment of NEDD8 to cullinsPlays a central role in autophagy (PubMed: 10604474, PubMed: 12372286, PubMed: 19270693, PubMed: 28445460). Acts as core subunit of different PI3K complex forms that mediate formation of phosphatidylinositol 3 phosphate and are believed to play a role in multiple membrane trafficking pathways: PI3KC3 C1 is involved in initiation of autophagosomes and PI3KC3 C2 in maturation of autophagosomes and endocytosis (PubMed: 19270693, PubMed: 25275521).