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Bohlhalter, S., Mohler, H

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One study (ITCA 650) reported as some concerns overall due to risk of bias in D2 due to concerns regarding the implantable device affecting the blinding of the procedure, which may have influenced how the intervention was administered (Fig

conducted a magnetic resonance imaging (MRI) study and found that long-term chronic hyperglycemia can mediate hippocampal dysfunction, 19 and hyperglycemia inflammatory mediators, rheological factors, and dysregulation of the hypothalamicpituitaryadrenal axis also may exacerbate cognitive decline