surmount-1 tirzepatide non-diabetic obesity trial once weekly for the treatment of in people with type 2 diabetes (SURMOUNT-2): a double-blind, randomised, multicentre, placebo-controlled, phase 3 Shifts in body mass index
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Shifts in body mass index category with tirzepatide and associated changes in cardiometabolic risk factors in people with obesity: a post hoc analysis from the SURMOUNT 1 and SURMOUNT 4 trials ScienceDirect For the first time, tirzepatide and semaglutide were put in the same trial. SURMOUNT 5. Phase 3b RCT. 751 adults with obesity, no diabetes. 72 weeks. Both drugs at maximum tolerated dose. The SURMOUNT 5 Trial: Tirzepatide vs Semaglutide in Obesity Management In the SURMOUNT 1 trial (published in NEJM in July 2022), adults with #obesity treated with weekly tirzepatide, a glucose dependent insulinotropic polypeptide and glucagon like peptide 1 receptor
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