PEG3 Polyclonal Antibody, 100ul Cell Culture Dishes nucleotide excision repair protein encoded

nucleotide excision repair protein encoded by RAD23B is one of two human homologs of Saccharomyces cerevisiae Rad23

The protein is weakly similar to transposase-like proteins in human and mouse

An aberrant form of this protein has been detected in patients with Alzheimer's disease and Down syndrome

Also component of the mSin3A complex which acts to repress transcription by deacetylation of nucleosomal histones

PEG3 Polyclonal Antibody, 100ul Cell Culture Dishes nucleotide excision repair protein encodedIn human, ZIM2 and PEG3 are treated as two distinct genes though they share multiple 5' exons and a common promoter and both genes are paternally expressed (PMID: 15203203). Alternative splicing events connect their shared 5' exons either with the remaining 4 exons unique to ZIM2, or with the remaining 2 exons unique to PEG3. In contrast, in other mammals ZIM2 does not undergo imprinting and, in mouse, cow, and likely other mammals as well, the ZIM2